The key commuter cut-through of Liverpool Street in Salford is to remain closed in both directions after a burst water main wrecked gas pipes.
Engineers were forced to close the road between Cross Lane and the Albion Way junction at around 6am on Tuesday 29 September.
United Utilities have been on site making repairs.
These were completed but around 3pm on Wednesday 30 September, but because the water leak damaged gas pipes, National Grid engineers will have to finish their own repairs before the road can be re-opened.
The extended repairs are expected to cause knock-on delays for traffic heading in and out of Manchester.
A spokesperson for Salford City Council said: “The road remains closed for now but Urban Vision will let the public know when it is expected to re-open, as soon as they have details.”