22-year-old Harvey Collins was reported missing from North Manchester General Hospital on Wednesday 1 April 2015.
Harvey is described as being Harvey is described as being around 5ft 8in tall, of stocky build and has short brown hair.
It is believed he was wearing a black hooded top, grey bottoms and blue trainers.
Officers understand he was heading towards Crumpsall tram stop and is known to frequent Manchester city centre.
Detective Constable Nick Kershaw said: “I am appealing for anyone may have seen
Harvey or knows where he is not to approach him but to contact Greater Manchester Police as soon as possible.
“His family have had no contact with him and he needs regular medication which he has not taken with him”.
“His loved ones are understandably concerned for his welfare and want him to contact us as soon as possible to let us know he is okay.”
Anyone with information as to where Harvey is should phone police on 101 or the independent charity Crimestoppers, anonymously, on 0800 555 111.